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Cellular Rejuvenation through Transcriptional Reprogramming

日期: 2023-07-24

北京大学定量生物学中心

学术报告 

题    目: Cellular Rejuvenation through Transcriptional Reprogramming

报告人:  Hao Li, PhD

Professor in the Dept of Biochemistry and Biophysics,

Director of the Hillblom Center for the Biology of Aging,

University of California San Francisco

时    间: 7月26日(周三)13:00-14:00

地    点: 吕志和楼B101

主持人: 韩敬东 教授

摘 要:

The idea of rejuvenation to counteract aging is as old as human civilization. For millennia, humankind has dreamt of rejuvenation therapies that could reverse aging, and tales of the fountain of youth have been recounted across continents. But, without a cellular level understanding of aging coupled with advanced intervention technologies, rejuvenation remained a fiction. Recent breakthroughs in aging research changed this situation drastically and brought us the hope that rejuvenation may become a reality. In this talk, I will describe some of the exciting progresses made in the field, and present our recent discovery of several novel transcription factors that can rejuvenate aged human fibroblast cells through transcriptional reprogramming.

报告人简介:

Dr. Hao Li is a Professor in the Dept of Biochemistry and Biophysics & the Director of the Hillblom Center for the Biology of Aging at UCSF. He is also a senior investigator of Chan Zuckerberg Biohub at San Francisco. He received his BS in Physics from Peking University and Ph.D. in theoretical physics from MIT. His current research focuses on molecular mechanisms of aging, systems biology, and human genetics.